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Advancing Aesthetics Together Technology
  • CD™ Cross-linking Technology
  • M-DOVETL™ Hybrid Technology
  • Hyaluronic Acid — The Molecule Of Rejuvenation
  • The Patented Cross-Linking
  • Recognize Molecular

Most Hyamax® products are formulated with hyaluronic acid, a molecule naturally present in the human body, particularly in the skin and mucous membranes. Renowned for its remarkable ability to retain up to 1,000 times its own weight in water, hyaluronic acid plays a critical role in maintaining tissue hydration, firmness, and overall skin vitality.

Due to its short half-life and high water solubility, hyaluronic acid requires stabilization before clinical use. This is achieved through a process known as cross-linking, in which HA molecules are interconnected to form a viscoelastic gel. The resulting gel provides long-lasting effects—such as smoothing, lifting, and volumizing the skin—that can persist for several months.

Laboratories Hyamed SA has developed CD™ Cross-linking Technology, an innovative method that combines both physical and chemical cross-linking of hyaluronic acid. This approach significantly reduces the amount of BDDE required while improving cross-linking efficiency. As a result, it enhances safety, minimizes HA degradation, and provides long-lasting performance with effects lasting up to 18 months.

For clinical applications aimed at lifting skin tissues and restoring volume, the HA gel must possess a unique combination of elasticity and viscosity to effectively respond to various mechanical stresses within the tissues. As a result, this technology optimizes the product's rheology, particularly by achieving a uniform cross-linked HA structure. It ensures the viscosity required for excellent injectability while increasing the density of chemical nodes. This guarantees the cohesion of the HA gel and maintains its monophasic properties.

High molecular weight HA raw material (2300 kDa), allowing it to align and self-entangle under physical stress.

  • Chemical cross-linking

  • Physical cross-linking

  • The Patented Hybrid Technology
  • Mechanism Of Action

M-DOVETL™ Hybrid technology is an advanced formulation method for hyaluronic acid that combines high and low molecular weight variants without chemical agents to enhance bioavailability and hydration. This innovative approach improves the absorption and utilization of hyaluronic acid in the skin, delivering deep moisture and long-lasting effects. Additionally, it optimizes rheological properties, ensuring balanced viscosity for better injectability and overall performance in both aesthetic and therapeutic applications.

Due to its short lifespan and water solubility, HA requires stabilization before being introduced into the skin. This is achieved through a procedure known as “cross-linking”, where HA molecules are connected to create a gel. This gel delivers effects such as smoothing, lifting, or adding volume to the skin, which can last several months

  • 32mg/ml (L-HA)
    < 350 kDa


    32mg/ml(H-HA)
    < 900 kDa

  • Fast Heating,breaks weak hydrogen bonds

  • Faster Cooling,hydrogen bonds to reform between H-HA and L-HA molecules

  • HA Complexes

    Thermally stabilized natural HA No BDDE or other chemical agents Biologically active

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