Can Hyamax® PLLA Filler Deliver Two Years of Facial Volume Restoration?

In the world of aesthetic medicine, the desire for lasting solutions has driven innovations beyond traditional fillers. While many dermal fillers provide immediate volume restoration, the trend is shifting towards treatments that stimulate natural collagen production. Enter the Hyamax® PLLA Injectable Poly-L-Lactic Acid Filler. Unlike typical volume boosters, it’s a collagen stimulator. Offering not just immediate improvement of skin texture, moisturizing and brightening of the skin,but biological revitalization,  which lead to a natural facial volume restoration for up to two years.  Let's explore the science behind this breakthrough.

The Science Behind PLLA: A Bio-Stimulatory Approach

PLLA (Poly-L-Lactic Acid) signifies a significant advancement from traditional volume replacement to bio-stimulation. Unlike traditional hyaluronic acid (HA) fillers, which plump the skin through physical filling and water attraction,, PLLA acts as a catalyst for collagen production. Upon injection, PLLA microparticles create a supportive framework beneath the skin. As the body gradually absorbs these particles, a natural inflammatory response is triggered, stimulating fibroblasts to produce new collagen. The outcome is long-lasting facial volume generated not by the filler itself, but by the body’s rejuvenated collagen.

The Mechanism of action (MOA) of PLLA

A Long-Lasting Solution: How Hyamax® PLLA Works

The claim of up to two years of results comes from the gradual bio-stimulation of collagen. Unlike temporary fillers, the collagen production process triggered by PLLA takes time, gradually building results over several months. This slow and natural regeneration leads to longer-lasting and more natural-looking improvements. The final result comes from your body’s own enhanced collagen matrix, not just the injected material.

The Dual Power of Hyamax® PLLA: Two Components for Maximum Effect

Hyamax® PLLA comes in a two-bottle system for optimal injection experience and results. Bottle A contains 150 mg of PLLA microspheres, the key collagen-stimulating agent.  Hyamax RUSH™ 3.0 PLLA Microsphere Technology provides optimal crystallization and molecular weight, ensuring a consistent degradation rate with effectiveness lasting up to 24 months. Bottle B contains 5 mL of non-crosslinked Hyaluronic Acid and lidocaine hydrochloride. This unique formula offers dual benefits: PLLA stimulates collagen production over time, while the HA provides immediate hydration, creating a smooth, plump appearance right after the procedure. The lidocaine ensures patient comfort during the injection process. Processed microspheres and a suitable vehicle allow for easy application; simply mix and shake before use. 

Who is Hyamax® PLLA For? 

Hyamax® PLLA is perfect for individuals with the following concerns: 

• Enlarged pores 
• Acne scars 
• Loss of skin volume 
• Dark circles and hollow under-eyes 
• Fine lines and wrinkles around the eyes and neck 
• Dry, dull skin that lacks radiance